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AstraZeneca announces results of TOPAZ-1 Phase III Trial

Imfinzi plus chemotherapy doubled overall survival rate at three years for patients with advanced biliary tract cancer in TOPAZ-1 Phase III trial Longest survival follow-up ever reported for immunotherapy treatment in this setting  Updated exploratory results from the TOPAZ-1 Phase III trial showed AstraZeneca’s Imfinzi (durvalumab) in combination with standard-of-care chemotherapy demonstrated a clinically meaningful long-term overall […]

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Takeda announces Compassionate Use Program for EXKIVITY

Takeda’s Compassionate Use Program for EXKIVITY is now open for enrollment in the U.S. The withdrawal of EXKIVITY will occur no later than March 2024, with the specific date still to be determined by the US Food and Drug Administration (FDA) based on review of ongoing operational activities related to the withdrawal. • Patients prescribed […]

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Merck provides new information on Treatment for Patients With Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma (MCC)

KEYTRUDA® (pembrolizumab) Injection 100 mg is indicated for the treatment of adult and pediatric patients with recurrent locally advanced or metastatic MCC. SELECTED SAFETY INFORMATION Severe and Fatal Immune-Mediated Adverse Reactions to exclude alternative etiologies, including infection. Institute medical management promptly, including specialty consultation as appropriate. 1 month. Consider administration of other systemic immunosuppressants in […]

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AstraZeneca shares the latest overall survival (OS) data for IMFINZI® in combination with IMJUDO®

AstraZeneca recently shared the latest overall survival (OS) data for IMFINZI® (durvalumab) in combination with IMJUDO®(tremelimumab-actl) for the treatment of adult patients with unresectable hepatocellular carcinoma (uHCC).1,2  Primary AnalysisThe primary analysis demonstrated statistically significant improvement in the primary endpoint of OS vs sorafenib in the first-line (1L) treatment of uHCC1,2: *The HR is based on the stratified Cox proportional hazards […]

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Takeda Provides Update on EXKIVITY® (mobocertinib)

Takeda has announced that following discussions with the U.S. Food and Drug Administration (FDA), we will begin the process of voluntarily withdrawing EXKIVITY (mobocertinib) from the U.S. market over the next few months. EXKIVITY is currently indicated for adult patients with epidermal growth factor receptor (EGFR) Exon20 insertion mutation-positive (insertion+) locally advanced or metastatic non-small […]

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New Data for TAGRISSO® (osimertinib) in the ADAURA Trial

AstraZeneca recently announced that new data from the ADAURA trial regarding AGRISSO® (osimertinib) has been released. The ADAURA trial is an ongoing study of TAGRISSO as adjuvant therapy after tumor resection in adult patients with completely resected Stage IB-IIIA EGFRm (exon 19 deletions or exon 21 L858R mutations) non-small cell lung cancer (NSCLC). TAGRISSO was approved as […]

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Register Now for OSCO’s “Best of” San Antonio Breast Cancer Symposium® Virtual Symposium to be held March 19, 2022

The Oklahoma Society of Clinical Oncology, Inc. would like to invite you to attend our 2022 Spring meeting. Join your colleagues to hear highlights from this state-of-the art symposium on the experimental biology, etiology, prevention, diagnosis and therapy of breast cancer and premalignant breast disease. The “Best of” SABCS is an officially licensed program of the San Antonio […]

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Novartis announces new treatment approval for SCEMBLIX®

Novartis is pleased to announce that SCEMBLIX® (asciminib) tablets is now approved for the treatment of adult patients with: ·  Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP), previously treated with 2 or more tyrosine kinase inhibitors (TKIs) ○     This indication is approved under accelerated approval based on major molecular response (MMR). Continued approval […]

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Oncopeptides withdraws Pepaxto® in US, scale down organization and focus on R&D

October 22, 2021     Subject: Voluntary withdrawal of PEPAXTO® (melphalan flufenamide) for the treatment of relapsed or refractory multiple myeloma   Dear Healthcare Provider:  This letter is to inform you about important information regarding PEPAXTO in the United States.  On October 22, 2021, Oncopeptides announced the decision to voluntarily withdraw the US accelerated approval for […]

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New life-changing survival data for women with HR+/HER2- metastatic breast cancer

Novartis is pleased to share new study results for KISQALI® (ribociclib), which now include overall survival (OS) data that no other CDK 4/6 inhibitor has yet reported: statistically significant OS in in first-line postmenopausal patients with an aromatase inhibitor.1 MONALEESA-2 was a dedicated first-line trial of KISQALI + letrozole vs placebo + letrozole in postmenopausal patients […]

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